We named this XL28-A. An in vitro luciferase assay revealed that XL28-A has no transcriptional activity. XL28-A was found in two unrelated patients with bipolar disorder in the CCSS and one healthy subject in the ACSS who did not show depressive symptoms or a decline in cognitive function. Therefore, it is unlikely that XL28-A is associated with…[Leer más]

Despite being the most common cause of secondary hypertension, prevalence of primary aldosteronism (PA) among patients with young-onset hypertension (YH – age of hypertension onset <40 years) remains poorly studied.

We assessed the prevalence of PA in patients with YH referred for evaluation of secondary hypertension.

In this…[Leer más]