Our in silico systems genetics approaches created two interaction networks consisting of densely-connected T1D and T2D loci genes. The «T1D-T2D islet eQTL interaction network» identified 9 genes (GSDMB, CARD9, DNLZ, ERAP1, PPIP5K2, TMEM69, SDCCAG3, PLEKHA1, and HEMK1) in common T1D and T2D loci that harbor islet eQTLs in LD with disease-associated…[Leer más]