The aim Women of reproductive age often think of motherhood and labor with fear of intense labor pain. The anxiety they experience can lead to their postponing pregnancy. There are not many studies in the literature that research the knowledge young women have about the analgesia of labor. The aim of the present work was to evaluate the state of awareness about the possible methods of labor analgesia among women of childbearing age.

Material and methods An Internet survey was conducted among 160 women. It consisted of questions on the pharmacological and non-pharmacological methods of labor analgesia. Most of the respondents were not medical university students (96.2%). Correct answers ranged between 11.3% and 97.5% of the total responses.

Results The greatest number of incorrect answers were given to the question regarding contraindications to labor anesthesia (only 11.3% of answers were correct). There was also a low percentage of correct answers to questions about the risk of spinal cord injury durinion on this topic.

Conclusions The study shows that women of childbearing potential have an unsatisfactory level of knowledge about labor anesthesia. There is a need to improve the level of health education on this topic.

The aim to study the possible role of psychosocial stressors in the emergence of anomalies of childbirth, as well as to examine their nature using the example of pregnant women who have been forcefully displaced from Donetsk and Luhansk regions of Ukraine.

Materials and methods 115 internally displaced pregnant women from Donetsk and Luhansk regions, were surveyed. All women underwent a comprehensive neuropsychological examination of their psycho-emotional status via interviews, questioning, and psychological testing (Spielberg-Haning’s Situational and Personal Anxiety Scale). The following analysis of the childbirth process’ nature was conducted.

Results The prevalence of high level of situational and personal anxiety by the Spielberg-Haning’s test were determined in the internally displaced women. This indicates a high level of social anxiety (stress) in these pregnant women. Labours in women in this group can be characterized by 3 main features rapid (precipitated) labour with high levels of obstetric traumatism (tear of perineum) and labour medicalization (EDA). The characteristics described above are due to such labour activity anomalies as hypertensive uterine dysfunction – the cases when the speed and strength of uterine contractions significantly exceed the normative parameters. The reasons for the high level of pain in labour in displaced women could be objecttive and subjective factors excessive nociceptor irritation due to cervical-uterine dysfunction and impaired individual perception of pain.

Conclusions Chronic psychosocial stress has an impact on labour activity in displaced women. A mandatory standard for managing such pregnancy is psychological counselling and correction of the identified disorders.

Conclusions Chronic psychosocial stress has an impact on labour activity in displaced women. A mandatory standard for managing such pregnancy is psychological counselling and correction of the identified disorders.

The aim to find out the effect of a two-hour tourniquets ischemia of the limb and acute blood loss on systemic disorders of the body in the postperfusion period.

Materials and methods The experiments were performed on 96 nonlinear male rats weighing 200-220 g. All experiments were performed under sodium thiopental anesthesia. In the first experimental group, two-hour tourniquets limb ischemia was simulated. In the second experimental group, acute blood loss was modeled. In the third experimental group, these lesions were combined. Act D In 1 and 2 hours, as well as in 1, 7 and 14 days, the biliary function of the liver was determined in the experimental animals.

Results Two-hour tourniquets ischemia of the limb in the reperfusion period compared with the control was accompanied by a significant decrease in the rate of bile excretion, which reached a minimum value in 3 h – 1 day of the experiment and returned to the control level in 14 days. After the simulation of acute blood loss, the rate disturbance of bile functional state of the liver, which is a significant decrease in the rate of bile excretion with a maximum in 1 day, which further increases, but up to 14 days does not reach the level of control.

Introduction Approximately 10% of fine needle aspiration biopsy (FNAB) of thyroid nodules may be verified as «suspicious for follicular neoplasm»; this category involves follicular adenoma, follicular carcinoma, follicular variants of papillary carcinoma and subclass «suspicious for Hurthle cell neoplasm». At present, there is no diagnostic tool to discriminate between follicular adenoma and cancer. Most patients are required surgery to exclude malignant process. The aim To define factors correlating with risk of malignancy in patients with FNAB of thyroid focal lesions and nodules verified as Bethesda tier IV.

Materials and Methods In this study 110 consecutive patients were included. All patients were operated because of FNAB result «suspicious for follicular neoplasm» of thyroid gland at a single institution from January 2016 until March 2020. From this set, six specific categories were defined and the clinical records for patients were collected sex, age, presence of oxyphilic cells, diameter of the te consider in every case as most appropriate manner to exclude thyroid cancer .

Introduction Polymeric substances, which are used in medicine, can lead to the development of pathological conditions. Therefore, in toxicological evaluation of polymeric materials for medical purposes the primary task is the creation of the appropriate adequate methods of study. The aim To studytheacinioftherats’submandibularsalivaryglandsin normalcondition andafter exposureof 1% methacrylate.

Material andmethodsWere studied 50 white rats during the influence of 1% methacrylate on the mucosa of the oral cavity. Histological sections of the rats’submandibularsalivary glands in normalcondition, on day 14 and 30 of experiment were studied using the UMPT – 7 ultramicrotome of Sumy PA «Selmi».

Results and conclusionsThemorphometric study hasestablishedthat in control group thevaluesof theouterdiameterof thesubmandibularglands’ acini, the diameter of the lumen and the height of the acini epithelial cells was 36,27±2,17 µm,9,47±0,63 µm and 14,18±1,05 µm, respectively. Histological specimens showed that the acini cells had a prominent basophilia of the cytoplasm and the basally located nucleus.